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Byung Churl Lee  (Lee BC) 56 Articles
Original Article
Analysis of gonadotropin-releasing hormone (GnRH) test results in girls with precocious puberty
Jung Yun Choi, Hyun-Ju Kang, Won Kyoung Cho, Kyoung Soon Kim, So Hyun Park, Seung Hoon Hahn, Min Ho Jung, Byung Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2009;52(12):1377-1382.   Published online December 15, 2009
Purpose : The gonadotropin-releasing hormone (GnRH) test results of girls with precocious puberty were analyzed to determine whether this test can efficiently and clearly differentiate between central precocious puberty (CPP) and other disorders. Methods : Clinical and laboratory data of 54 girls with precocious pubertal signs were reviewed. Intravenous GnRH test was performed with blood samples obtained at 0, 30,...
Serum ghrelin and leptin concentrations in children with cancer : comparisons with normal children
So Hyun Park, Min Ho Jung, Nac Gyun Chung, Byung-Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2007;50(9):905-911.   Published online September 15, 2007
Purpose : Ghrelin, being secreted from the stomach, stimulates growth hormone secretion and controls energy homeostasis by increasing appetite. Leptin, being secreted from the adipocytes, controls weight and energy homeostasis by decreasing appetite. Leptin concentration is reported to increase after childhood cancer therapy. This study was aimed to compare ghrelin and leptin concentrations in normal children and children who received...
Case Report
A case of adrenocortical adenoma following long-term treatment in a patient with congenital adrenal hyperplasia
Seung Rim Lho, So Hyun Park, Min Ho Jung, Byung Churl Lee
Clin Exp Pediatr. 2007;50(3):302-305.   Published online March 15, 2007
As a result of the widespread use and enhanced quality of high-resolution radiological techniques, a recent report has revealed a relatively high prevalence of small adrenal tumors in patients with untreated congenital adrenal hyperplasia due to 21-hydroxylase deficiency. However, there are scarcely any pediatric cases of adrenocortical tumor following long-term treatment in patients suffering with congenital adrenal hyperplasia. We report...
Original Article
Correlations of cord blood Ghrelin and leptin concentrations with anthropometry of appropriate for gestational age newborns
Jin Lee, Se Na Moon, So Hyun Park, Min-Ho Jung, Byung Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2006;49(1):93-98.   Published online January 15, 2006
Purpose : Ghrelin stimulates the secretion of growth hormone and other pituitary hormones, and has orexigenic effects. It may have a physiologic role in fetal and neonatal growth. Leptin secreted by the adipocytes reflects fat mass in infants as well as adults. The aim of this study was to evaluate the relation of cord blood ghrelin and leptin levels to...
Tumor Necrosis Factor and Lymphotoxin-α Gene Polymorphism in Korean Children with Type 1 Diabetes
Jin Soon Suh, So Young Park, Min Ho Jung, Byung Kyu Suh, Tae Gyu Kim, Byung Churl Lee
Clin Exp Pediatr. 2005;48(8):871-876.   Published online August 15, 2005
Purpose : Recently, it was reported that tumor necrosis factor(TNF) and lymphotoxin-α(LT-α) gene regions might be a susceptible loci to type 1 diabetes in Japanese. The purpose of this study was to investigate the association of TNF and LT-α gene polymorphisms with disease susceptibility in Korean children with type 1 diabetes. Methods : Forty-nine Korean children with type 1 diabetes(29...
Case Report
A Case of Cystinosis
Min Ho Jung, Seung On Keun, Soon Ju Lee, Byung Churl Lee
Clin Exp Pediatr. 2003;46(6):615-619.   Published online June 15, 2003
Cystinosis, an autosomal recessively inherited lysosomal storage disease, results from impaired transport of the amino acid cystine out of cellular lysosomes. The consequent accumulation and crystallization of cystine destroys tissues, causing growth retardation, Fanconi syndrome, renal failure, eye problems, and endocrinopathies. The gene for cystinosis, CTNS, was mapped to chromosome 17p13. The diagnosis of cystinosis was made by measuring the...
Original Article
Graves` Disease in Prepubertal Children Compared with Pubertal Children
Hyun Mi Kim, Ju Yun Yoon, Min Ho Jung, Byung Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2003;46(1):76-82.   Published online January 15, 2003
Purpose : The aim of this study was to determine whether differences exist in the presentation, clinical course, and outcome of Graves' disease between prepubertal children and adolescents. Methods : A retrospective chart review of 14 prepubertal(PREPUB, 7.2?.9 yr) and 38 pubertal (PUB, 12.4?.5 yr) children with Graves' disease between January 1989 and November 1995 at St. Mary's Hospital and Kangnam...
Changes of Bone Metabolism Markers and Bone Mineral Density with Improvement of Thyroid Function in Children and Adolescents with Hyperthyroidism
Min Ho Jung, Choong Ho Shin, Sei Won Yang, Byung Churl Lee
Clin Exp Pediatr. 2002;45(6):743-753.   Published online June 15, 2002
Purpose : Dynamics of bone mineral density(BMD) and bone metabolism in children and adolescents with hyperthyroidism have not been thoroughly investigated. The aim of this study was to study how the improvement of thyroid function with antithyroid treatment influenced bone metabolism and BMD in children and adolescents with hyperthyroidism. Methods : Serum levels of osteocalcin(OC), bone-specific alkaline phosphatase(b-ALP), and carboxyterminal telopeptide...
Case Report
A Case of 18 Ring Chromosome
Joong Hyun Bin, Moon Young Song, In Goo Lee, Won Bae Lee, Byung Churl Lee
Clin Exp Pediatr. 2001;44(6):683-686.   Published online June 15, 2001
A ring 18 chromosome(18r) karyotype is a rare disorder characterized by short stature, obesity, microcephaly, mental retardation, micropenis, cryptorchidism, hypertelorism, epicanthal folds, micrognathia, and small hands with short tapering fingers. A 22-month-old girl was referred to our department of pediatrics because of ptosis and delayed development. Karyotype revealed ring 18 and dicentric ring 18 chromosome(46,XX,r(18)[45]/45,XX,-18[7]/46,XX,dic r(18)[3]). Fluorescent in situ hybridization...
Original Article
Final Height in Idiopathic Growth Hormone(GH) Deficient Children Treated with GH
Byung Churl Lee
Clin Exp Pediatr. 1999;42(6):852-857.   Published online June 15, 1999
Purpose : Improved adult height is a major goal in the treatment of children with short stature due to GH deficiency(GHD). The purpose of this study was to evaluate final height in idiopathic GH deficient children after long-term GH treatment Methods : GHD was diagnosed in 9 male patients by at least two stimulation tests(maximum GH level≤5ng/ml). Other pituitary functions were...
Neonatal Cord Blood Leptin : Its Relationship to Birth Weight
Byung Churl Lee, In Kyung Sung, Byung Kyu Suh, Moon Young Song
Clin Exp Pediatr. 1999;42(5):637-643.   Published online May 15, 1999
Purpose : The purpose of this study was to correlate birth weight, skinfold thickness, gestational age, BMI and ponderal index of neonates and maternal status with cord serum leptin concentration. Methods : Sixty newborns were enrolled in this study. Standard growth curves were used to categorize infants as appropriate(AGA), large(LGA), or small for gestational age(SGA). Gestational age, birth weight, length, skinfold...
Serum Leptin Levels in Children with Obesity
Byung Churl Lee, Moon Young Song, Byung Kyu Suh
Clin Exp Pediatr. 1998;41(6):785-790.   Published online June 15, 1998
Purpose : The identification of the ob gene and its adipocyte-specific protein leptin has provided the first physiologic links to the regulatory system controlling body weight. In adults, elevations of serum leptin concentrations correlated closely with the percentage of body fat. This study investigated whether leptin concentrations were elevated in obese children, and the relationship between leptin concentrations and gender and pubertal stage. Methods :...
Clinical Lecture
Enuresis
Byung Churl Lee
Clin Exp Pediatr. 1998;41(11):1471-1475.   Published online November 15, 1998
Original Article
Long-term Growth Response to Growth Hormone Therapy in Children with Growth Hormone Deficiency
Byung Churl Lee
Clin Exp Pediatr. 1997;40(5):672-679.   Published online May 15, 1997
Purpose : The aim of this study was to evaluate the long-term growth response to growth hormone therapy in 18 children with naive growth hormone deficiency. Methods : The subjects of this study were aged 3-13.5 years and each patient continuously received GH(EutropinⓇ) 0.45-0.7IU/kg/week, intramuscularly or subcutaneously in 3-7 divided dose for up to 7 years. Standard auxologic assessment was carried...
Clinical Study of Graves` Diseasein Children : Remission and Relaps
Moon Young Song, Bin Cho, Byung Churl Lee
Clin Exp Pediatr. 1996;39(3):389-396.   Published online March 15, 1996
Purpose : This study was carried out to evaluate the age and sex distribution, clinical manifestation, presence of the antithyroid antibody, the clinical outcome following antithyroid drug treatment in children with Graves' disease. Methods : A total 45 children with Graves' disease were entered into the study. Diagnosis was based on clinical manifestation, elevated thyroid function and increased homogeneous 99mTc thyroid...
Case Report
Two Siblings of Non Salt Losing Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency
Seung Cheol Lee, Byung Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 1995;38(4):574-581.   Published online April 15, 1995
Congenital adrenal hyperplasia in caused by a defect in the biosynthesis of cortisol as a result of deviciency in one of the essential enzymes, most commonly 21-hydroxylase and is an autosomal recessive disease in close genetic linkage with HLA. The common clinical manifestations of congenital adrenal hyperplasia is progressive virilization in both sexes, abnormal external genitalia in the...
Original Article
Responses to Growth Hormone Treatment in Children with Short Stature Secondary to Intrauterine Growth Retardation
Byung Churl Lee, Dong Won Kin, Byung Kyu Suh
Clin Exp Pediatr. 1995;38(12):1671-1676.   Published online December 15, 1995
Purpose : Several studies recently have emphasized the value of sonography as an new therapeutic method for hydrostatic reduction of intussusception by using a saline enema under ultrasound guidance. The purpose of this study was to asses the diagnostic screening efficacy of sonography in suspected childhood intussusception and the value of ultrasound guidance in hydrostatic reduction performed with saline enema. Methods...
Case Report
Two Male Siblings with Pseudohypoaldosteronism Type I
Ran Lee, Sang Yong Kim, Sung Dong Choi, Seung Yun Chung, Jin Han Kang, Byung Churl Lee
Clin Exp Pediatr. 1994;37(2):262-268.   Published online February 15, 1994
Pseudohypoaldosteronism (PHA) is rare herediary salt wasting syndrome due to peripheral resistance to aldostrone. PHA type I, subdivided into isolated renal insensitivity to aldosterone of autosomal dominant inheritance and multiple target organ defect of autosomal recessive inheritance, and PHA type II show similar clinical manifestations except hypertension which is limited to type II. PHA type I is charaterized by hyponatremia, hyperkalemia,...
A Case of Distal Renal Tubular Acidosis
Bin Cho, Dong Sung Kim, Byung Churl Lee
Clin Exp Pediatr. 1994;37(1):115-112.   Published online January 15, 1994
Distal renal tubular acidosis (RTA) is a biochemical syndrome as a dificiency of hydrogen ion secretion by the distal tubule and collecting duct. Owing to the nature of the defect, hyperchloremic non-anion gap metabolic acidosis and high urine pH despite severe systemic acidosis is characterized. Typical manifestations of distal RTA are growth retardation, rickets, polyuria and nephrocalcinosis. We experienced a case of...
A Case of Bile Peritonitis Due to Spontaneous Perforation of Choledochal Cyst in Infant
Yong Gi Kim, Byung Chan Lee, Woo Gun Choi, Byung Churl Lee, Kyong Su Lee
Clin Exp Pediatr. 1993;36(7):1039-1043.   Published online July 15, 1993
Bile peritonitis due to spontaneous perforation of choledochal cyst is a rare disease and the etiology of spontaneous perforation is unknown in most of infant cases. Recently, we experienced a case of bile peritonitis caused by spontaneous perforation of choledochal cyst in a 6 month-old female infant. She had progressive abdominal distention with ascites, mild jaundice and intermittent passage of acholic...
A Case of Virilizing Adrenocortical Adenoma
Seung Hee Lee, Gwang Goog Min, Byung Churl Lee
Clin Exp Pediatr. 1993;36(2):292-297.   Published online February 15, 1993
This is a case report of virilizing adrenal cortical adenoma in 22 month old male patient who was diagnosed by clinical features, endocrinological studies, radiologic studies and pathologic findings. During surgery, a 40gm well-encapsulated tumor was removed from the right adrenal gland. Histologic examination revealed no capsulr invasion and a diagnosis of adrenocortical adenoma was made. He is in well condition...
A Case of McKusick-Kaufman Syndrome
Han Joo Kong, Young Mi Jee, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1992;35(6):829-833.   Published online June 15, 1992
We experienced a case of Mckusick-Kaufman syndrome in a 14 day-old female neonate. She had hydrometrocolpos with vaginal atresia and polydactyly of feet associated with bilateral hydronephrosis and umbilical hernia. Hydronetrocolpos with vaginal atresia was corrected by abdominoperineal-vaginal pull through operation on 21st day of life. A brief review of related literatures was made.
A Case of Unilateral Absence of Pulmonary Artery
Joon Ho Bang, Sang Nyen Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(6):873-878.   Published online June 15, 1992
A Unilateral Absence of Pulmonary Artery(UAPA), which develops occasionally as one of the associated anomaly in congenital cardiovascular defect like as tetralogy of Fallot, is rare anomaly as an isolated congenital defect. We have recently experienced a case of UAPA in a 9 years old boy, which was diagnosed by perfusion scan, digital subtraction angiography. So we report this case...
A Case of Cloacal Deformity
Young Mi Jee, Seung Jin Lee, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1992;35(5):667-670.   Published online May 15, 1992
We experienced a case of cloacal deformity. This one day-old female neonate had hydrometrocolpos with vaginal atresia, imperforated anus, cloaca associated with hemivertebrae, left renal agenesis and right hydronephrosis. A brief review of related literature was made.
Acute Disseminated Encephalomyelitis
So Young Kim, Jong Woo Bae, Byung Churl Lee
Clin Exp Pediatr. 1992;35(5):671-677.   Published online May 15, 1992
Acute disseminated encephalomyelitis is an uncommon immune mediated inflammatory disorder of the central nervous system. It may be defined as a monophasic encephalitis or myelitis of abrupt onset characterized by symptoms and signs indicative of damage chiefly of the white matter of the brain or spinal cord. The process may be severe and even fatal or mild and evanescent. The...
Two Cases of Congenital Hepatic Fibrosis
Cue Jung Hwang, Young Hun Kim, Dae Kyun Koh, Byung Churl Lee
Clin Exp Pediatr. 1992;35(4):569-574.   Published online April 15, 1992
The congenital hepatic fibrosis is a rare condition defined pathologically by the presence within the line of bands of fibrous tissue which after contain linear or circular spaces lined by bile duct cells, It is commonly associated with intrahepatic portal hypertension but hepatocellular function is almost always preserved. The prinicipal clinical features of this disease are abdominal distension, firm hepatomegaly,...
Original Article
The Pharmacokinetics and Biological Effects of Yeat Dervied Recombinant Methionyl Growth Hormone in growth Hormone Deficient Children
Byung Churl Lee
Clin Exp Pediatr. 1992;35(3):349-354.   Published online March 15, 1992
The parmacokinetics and biological effects of an recombinant methionyl growth hormone(LBD-003) produced by the expression of genomic hGH in a yeast cell line, were studied in growth hormone deficient children. Twelve patients were randomly assigned to two age-matched subcutaneous and intramuscular groups. Each group consists of 6 patients. Each subject received an dosage of 0.1 U hGH(LBD-003)/kg, BW, Blood was drawn before...
Case Report
Subacute Necrotizing Encephalomyelopathy (=Leight's Disease)
So Young Kim, Heung Ki Min, Byung Churl Lee
Clin Exp Pediatr. 1992;35(3):395-398.   Published online March 15, 1992
Subacute necrotizing encephalomyelopathy or Leigh's disease is a familial neurodegenerative disorder characterized by focal bilateral and usually symmetric lesions of both gray and white matter in the brain and the spinal cord. The lesions are strikingly similar to those of thiamine deficiency encephalopathy. The diagnosis of subacute necrotizing encephalomyelopathy was usually made by typical clinical manifestation and typical bran CT...
Two Cases of Hemimegalencephaly
Hee Sun Yang, Bin Jo, Seung Hoon Seung, Jong In Byun, Won Bae Lee, Byung Churl Lee, Snng Hoon Cho, Il Kwon Yang
Clin Exp Pediatr. 1992;35(11):1584-1589.   Published online November 15, 1992
Hemimegalencephaly is a rare brain malformation characterized by congenital hypertrophy of one cerebral hemisphere with ipsilateral increased volume of the white matter and dilatation of the lateral ventricle. We have experienced two cases of hemimegalencephaly in neonates who were admitted because of repetitive seizure. One case was simple hemimegalencephaly and the other case was combined by corpus callosum agenesis. Diagnosis was...
Original Article
The Factors on the Development of Coronary Arterial Involvement in Kawasaki Disease
Sang Yen Kim, Jong Hyun Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyung Tai Whang, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(10):1328-1335.   Published online October 15, 1992
In Kawasaki disease, coronary arterial involvement is an important prognostic factor. Many studies have reported about risk factors of coronary artery disease in Kawasaki disease. This study was designed to evaluate factors influencing coronary arterial involvement and to evaluate the effect of intravenous gammaglobulin (IVG) when admitted on the widely used criteria in Korea. Fiftyfour patients meeting the CDC criteria...
Clinical effects of yeast derived recombinant methionyl growth hormone in growth hormone deficiency.
Byung Churl Lee
Clin Exp Pediatr. 1991;34(3):334-339.   Published online March 31, 1991
Since the success of human growth hormone (hGH) synthesis by recombinant DNA technology, these GH products are used in the treatment of growth hormone deficiency. Recently, methionyl-GH has been produced in the yeast, Saccharomyces cerevisiae 2150 by the use of a recombinant method. In this paper, the clinical efficacy and. immunogenicity of this GH was studied during therapy of 1 year in 20 children...
Clinical Obervation in 40 Cases with Neonatal Sepsis.
Jung Hee Lee, Jae Jin Park, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1990;33(11):1489-1494.   Published online November 30, 1990
Sepsis is still one of major causes of mortality and morbidity in neonatal period and early diagnosis and appropriate treatment for neonatal sepsis is difficult due to its vague clinical manifestation and rapid progress. An analysis of 40 cases of neonatal sepsis confirmed by clinical manifestation and blood cultures from Jan. 1986 to Dec. 1989 at nursery of St. Mary’s Hospital of Catholic University...
Mechanical Ventilation in Newborn Infants.
Young Back Hahm, Jong Ho Sung, In Kyung Sung, Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1990;33(1):10-21.   Published online January 31, 1990
Clinical analysis of 5 years* experience with mechanical ventilation of 68 neonates in NICU of St. Mary’s Hospital, from Jan. 1983 to June 1988, was done. The results were as follows; 1) Indications for mechanical ventilation were hyaline membrane disease(51.5%), postasphyxia syndrome(19.1%), apnea of prematurity (5.9%), sepsis (5.9%), intracranial hemorrhage (5.9%) and others. 2) Number of male patients was 33(48.5%》and of female was 35(51.5%), and male to female...
A Case of True Hermaphroditism.
Hi Young Chun, Won Suk Suh, Byung Churl Lee
Clin Exp Pediatr. 1989;32(8):1174-1179.   Published online August 31, 1989
A hermaphrodite in an individual in whom both testicular and ovarian tissues are present. A 15-year old boy presented with breast development and hypospadias. On physical examination, his height, weight, and arm span were normal. He had stage 4 breast development and normal pubic (stage 4) and axillary hair. He also had hypospadias in spite of corrective surgery 2 times. And his karyotype was...
A Case of the Hepatoblastoma with Precocious Puberty.
In Young Park, Byung Jun Lee, Byung Churl Lee
Clin Exp Pediatr. 1989;32(5):735-740.   Published online May 31, 1989
Hepatoblastoma is a rare neoplasm in childhood. Hepatoblastoma associated with precocious puberty caused by human chorionic agonadotropin (HCG) secreted by the tumor itself, is very rare. We experiened a case of hepatoblastoma with precocious puberty in a 28-month-old boy, who was admitted because of abdominal pain, enlarged testis & penis, pubic hair and a deep voice. Diagnosis was made by typical Clinical manifestation, elevated...
Two Siblings of Congenital Hypothyroidsm due to Organification Defect.
Young Kie Park, Kwang Sun Park, Byung Churl Lee
Clin Exp Pediatr. 1989;32(4):582-588.   Published online April 30, 1989
Congenital hypothyroidism due to a variety of defects in the biosynthesis of thyroid hormone is detected in 1/30,000-50,000 live births. In the iodide organification defect which is one of defect in the biosynthesis of thyroid hormone, iodide is not organified and may be rapidly discharged from the thyroid by administration of perchlorate. We experienced two siblings who had short stature, goiter, mental retardation, constipation and other...
A Case of Chondrodysplasia Punctata of the Rhizomelic Type.
Ki Sik Min, Bo Kyung Cho, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1989;32(1):87-91.   Published online January 31, 1989
Chondrodysplasia punctata is a rare familial disorder of bone, characterized by punctate calcifica- tion in the epiphyseal regions. We experienced a case of the rhizomelic type of chondrodysplasia punctata in an one day old female. She had symmetrical shortening of the proximal limbs, flexion contracture of both hip joints, cataracts and ichthyotic skin lesion. Radiologic findings showed multiple stippled calcified densities in most joints and...
One Case of Pheochromocytoma.
Jong Jin Kim, Jung Oh Kim, Sung Won Kang, Byung Churl Lee
Clin Exp Pediatr. 1988;31(7):942-947.   Published online July 31, 1988
The Pheochromocytoma is a rare tumor of childhood and can arise from chromaffin tissue anywhere in the body. Most commonly it is located in the adrenal medulla, especially on the right side. We experienced a case of pheochromocytoma in a 14 year old boy, who had paroxysmal palpitation, perspiration, dyspnea and contemporary paroxysmal hypertension. Diagnosis was made by clinical features, elevated plasma catecholamine concentration,...
A Case of Acute Hepatic Porphyria.
Young Cheal Han, Sin Hang Joo, Jin Han Kang, Byung Churl Lee
Clin Exp Pediatr. 1988;31(2):253-257.   Published online February 28, 1988
Acute hepatic porphyria may be an inborn error of metabolism characterized biochemically by the excessive hapatic over-production and urinary excretion of porphyrin precursors and clinically by episode of acute neuro-visceral dysfunction. Acute porphyria is very rare in childhood. We experienced a case of acute hepatic porphyria in childhood age, confirmed by characterized clinical features of neuro-visceral dysfunction and biochemical findings in blood and urine...
A Case of Primary Hyperparathyroidism in Childhood.
Dong Sung Kim, Soon Joo Lee, Kyung Il Lee, Byung Churl Lee
Clin Exp Pediatr. 1988;31(10):1350-1357.   Published online October 31, 1988
Primary hyerparathyrodism is rare in children under the age of sixteen and is characterized by conspicuous skeletal and renal changes. An 11 years old male patient who had complained of severe lower back pain, nausea and vomiting since last 3 months, showed typical laboratory and radiological findings of primary hyperparathy roidism. Confirmatory diagnosis was made by elevated serum parathyroid hormone concentration, imaging method by technetium-thallium subtraction...
Clinical Analysis of Congenital Malformations in the Newborn Infant.
Hoon Chang, Chae Hwa Lee, In Kyung Sung, Byung Churl Lee, Sung Hoon Cho
Clin Exp Pediatr. 1988;31(1):72-77.   Published online January 31, 1988
Congenital malformations are still one of the leading problems of neonatal death and illness. But, we have only a few data for about it, because of difficulty in the exact analysis of the incidence and etiologic factors. During the period of 6 years, between January 1980 and December 1985, a clinical study about the general incidence of congenital malformations was done on 50, 979...
Statistical Observations for Pediatric Inpatients.
Byung Cheol Han, Hack Ki Kim, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1987;30(4):385-392.   Published online April 30, 1987
We observed the patients admitted to the department of pediatrics of St. Mary*s Hospital, Catholic Medical College during the past 20 years from Jan. 1966 to Dec. 1985 and classified them by year and disease according to the International Classification of Disease by W.H.O. (1965 Revision). The results were as follows: 1) The total number of pediatric inpatients during 20 years was 18,686, of which...
Clinical Study of Congenital Hypothyroidism.
Byung Churl Lee, Soon Joo Lee, Sung Hoon Cho
Clin Exp Pediatr. 1987;30(12):1401-1408.   Published online December 31, 1987
We reviewed 24 patients with congenital hypothyroidism to observe the etiology, clinical symptoms and signs, bone age, height age, the degree of mental retardation and growth velocity after treatment form Jan. 1983 to June 1987. The results were as follows: 1) The male to female ratio was about 1:3.8. The cases diagnosed under 1 year old were only 12.5%. 2) In etiologic classification, thyroid dysgenesis...
Case Report
A Case of Poland Syndrome.
Jong Deok Kim, Hyung Kook Ki, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1987;30(1):99-101.   Published online January 31, 1987
The Poland syndrome consists of congenital unilateral absence of the pectoralis major muscle and ipsilateral anomalies of the hand, typically syndactyly. It may be combined with many other anomalies. Recently, we experienced an 8 days old boy, who had the total absence of the metacarpals and phalanges of left hand and defect of the pectoralis muscle on the same side. A brief review of the...
A Case of Chondroma in the Mediastinum.
Hyun Mee Lee, Jin Oh Lee, Hack Ki Kim, Byung Churl Lee
Clin Exp Pediatr. 1986;29(10):1143-1146.   Published online October 31, 1986
Most chondroma often occur within or on the surface of the tubular bone and soft tissue, and are also found in many organs, but it is extremely rare in the mediastinum. Recently, we experienced a case of chondroma of the middle mediastinum, in a 13-years old girl with intermittent chest discomfort and exertional dyspnea for several months. Diagnosis was made by...
Three Cases of Renal Tuberculosis in children.
Young Hwa Joung, Kyoung Soo Kim, Sung Won Kang, Kyu Hong Cho, Byung Churl Lee
Clin Exp Pediatr. 1985;28(9):916-921.   Published online September 30, 1985
Kidney tuberculosis is serious complication during childhood just as later life because the disease tends to invade and to destroy both kidney. We reported three cases of renal tuberculosis in 8-yr-old female, 10-yr-old female and 6- yr-old male child. Case 1 and 3 had complaints of continuous fever and poor appetite and case 2 had complaints of dysuria and urinary...
A Case of Acute Lymphocytic Leukemia Successfully Treated with Allogeneic Bone Marrow Transplantaion.
In Kyung Sung, Byung Churl Lee, Kyong Su Lee, Du Bong Lee, Chong Won Park, Chun Choo Kim, Dong Jip Kim
Clin Exp Pediatr. 1985;28(8):805-811.   Published online August 31, 1985
A 8-year old boy with acute lymphocytic leukemia who had shown resistance to repeated combination chemotherapies, was successfully grafted with bone marrow from his HLA- matched sister. He was in the third partial remission at the time of bone marrow transplantation. He was conditioned with cyclophosphamide 60 mg/kg/day on two consecutive days, followed by 800 rads total body irradiation. Marrow...
Original Article
Neonatal Mortality Rate.
Byung Kyu Suh, Dong Ku Lee, Byung Churl Lee
Clin Exp Pediatr. 1984;27(5):425-432.   Published online May 31, 1984
A statiscal study on 18,679 newborns who were born in pediatric department of ST. MARY’S Hospital, ST. PAUUS Hospital, Kang-Nam ST. MARY*S Hospital and OUR LADY OF MERCY Hospital in Catholic Medical College from January, 1980 to December, 1982 was performed. Authors studied the mortality rate by birth weight, gestational period, sex, time after birth, Apgar score, mode of delivery...
Epidemiologic and Clinical Study of Mucocutaneous Lymphnode Syndrome in Korea.
Du Bong Lee, Kyong Su Lee, Byung Churl Lee, Ik Jun Lee
Clin Exp Pediatr. 1982;25(10):977-993.   Published online October 31, 1982
Mucocutaneous Lymphnode Syndrome (MCLS) becomes familiar to pediatrician recently as a new disease entity. However, the pathogenesis of this syndrome is not know yet. Since Dr. Kawasaki’s first cases had reported in 1963, over 30,000 cases of this disease has "been reported in Japan. This study was undertaken to know the epidemiologic status of this dis- ease in this country. The materials were collected from...
Epidemiological Study on Diseases of Korean Children in Urban & Rural Areas.
Du Bong Lee, Sung Hoon Cho, Kyong Su Lee, Byung Churl Lee
Clin Exp Pediatr. 1980;23(3):173-197.   Published online March 15, 1980
This study was attempted to know the recent changes of the patterns of diseases among Korean children living inurban and rural areas. 21,498 sick-children, who admitted to the thirteen general hospitals which located in urban and rural areas during past five years from Jan. 1994 to Dec. 1978, were analysed for this purpose. 13,759 sick-children(64.0%) were male, others were female...
Clinical Observation of Type A Hepatitis in Children.
Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1979;22(3):213-222.   Published online March 15, 1979
We observed 241 cases of type A hepatitis who were admitted to pediatric department of St. Mary`s Hospital, Cathlic Medial College from Jan. 1,1968 to Dec. 31,1977, and the following results were obtained. 1. Annual incidence was the highest in 1975 and lowest in 1969, but wr observedno significant difference. 2. Seasonal incidence was high in Autumn and Winter, and...
Feeding Results of Maeil Dry Milk G-80 in Low Birth Weight Infants.
Yong Eun Jung, Hyo Sup Kim, Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1979;22(11):956-960.   Published online November 15, 1979
The low birth weight infants have been fed with 15% concentration of Maeil Dry Milk G-80(Table 1) until the date of weight gaining to 2.5kg at the nursery room of our pediatric department, St. Mary's Hospital, Catholic Medical College. Feeding results were obtained as follows. 1. General physical condition was fair. The initial weight loss was average 6.8% of their...
Clinical Evaluation of Children with Psychiatric Problems among Pediatric Patients.
Kyung Tai Whang, Byung Churl Lee, Sung Hoon Cho, Haeng Sook Kim
Clin Exp Pediatr. 1978;21(3):198-206.   Published online March 31, 1978
Patients who visited to the pediatric department sometimes present psychiatric problems, but this interesting field seems to have been neglected frequently by clinicians. The authors were analyzed 130 cases of pediatric patients who referred to psychiatric department for the evaluation of psychiatric problems from July, 1974 to June, 1977 at the St. Mary's hospital, Catholic medical college. The results were...
Case Report
A Case of Juvenile Rheumatoid Arthritis
Tae Kyoo Park, Byung Churl Lee, Jae Chung Lee, Sang Duck Cha
Clin Exp Pediatr. 1973;16(5):397-401.   Published online May 31, 1973
We have experienced a case of juvenile rheumatoid arthritis in 5 year and 4 months old female. She had multiple subcutaneous nodules and arthralgia with fever on admission. The diagnosis was established by clinical, laboratory and X-ray findings. The pertinent literature are reviewed briefly.
Case Report
A Case Report of Cleidocranial Dysostosis
Byung Churl Lee, Tae Kyoo Park, Chung Kyu Kim, Kee Tae Kim
Clin Exp Pediatr. 1973;16(4):341-344.   Published online April 30, 1973
We experienced a new form of cleidocranial dysostosis. Patient is characterized by absence of the both clavicles, defective and limitted ossification of calvarium, limitted ossification of both pubic and ischiac bone. A brief review of literature was made.
Case Report
Two Cases of Idiopathic Dilatation of the Common Bile Duct
Jung II Kim, Byung Churl Lee, Young Joon Kim, Sang Duk Cha
Clin Exp Pediatr. 1972;15(11):1053-1057.   Published online November 30, 1972
Authors had experienced 2 cases of idiopathic dilatation of the common bile duct which was diagnosed by clinical, laboratory, X-ray and surgical findings. CaseⅠ in 4 years old girl has been observed for 1 ½ years after choledochoduodenostomy and caseⅡ in 10 years old boy has been followed up for 6 months after choledochojejunostomy (Roux-en-Y) without any complications. The review of the literature was...
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